granulocyte-macrophage colony-stimulating factor

A cytokine protein secreted by macrophages, T cells, mast cells, endothelial cells and fibroblasts.

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  • granulocyte-macrophage colony-stimulating factor — n a colony stimulating factor produced by T cells, macrophages, endothelial cells, and fibroblasts that promotes the differentiation of bone marrow stem cells, stimulates the maturation of precursor cells into granulocytes and macrophages, and… …   Medical dictionary

  • Granulocyte macrophage colony-stimulating factor — Not to be confused with granulocyte colony stimulating factor. Colony stimulating factor 2 (granulocyte macrophage) PDB rendering based on 2gmf …   Wikipedia

  • granulocyte-macrophage colony-stimulating factor — noun : a colony stimulating factor produced by T cells, macrophages, endothelial cells, and fibroblasts that promotes the differentiation of bone marrow stem cells, stimulates the maturation of precursor cells into granulocytes and macrophages,… …   Useful english dictionary

  • granulocyte-macrophage colony-stimulating factor — GM CSF. A substance that helps make more white blood cells, especially granulocytes, macrophages, and cells that become platelets. It is a cytokine that is a type of hematopoietic (blood forming) agent. Also called GM CSF and sargramostim …   English dictionary of cancer terms

  • Granulocyte macrophage colony-stimulating factor receptor — The granulocyte macrophage colony stimulating factor receptor also known as CD116 (Cluster of Differentiation 116), is a receptor for granulocyte macrophage colony stimulating factor, which stimulates the production of white blood cells. The… …   Wikipedia

  • Macrophage colony-stimulating factor — Colony stimulating factor 1 (macrophage) PDB rendering based on 1hmc …   Wikipedia

  • Colony-stimulating factor — Colony stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of hemopoietic stem cells, thereby activating intracellular signaling pathways that can cause the cells to proliferate and differentiate… …   Wikipedia

  • Granulocyte colony-stimulating factor — Not to be confused with granulocyte macrophage colony stimulating factor. Colony stimulating factor 3 (granulocyte) Crystal structure of 3 molecules of human G CSF. From PDB …   Wikipedia

  • Granulocyte colony-stimulating factor receptor — The granulocyte colony stimulating factor receptor (G CSF R) also known as CD114 (Cluster of Differentiation 114), is a cell surface receptor for the granulocyte colony stimulating factor (G CSF).cite web | title = Entrez Gene: CSF3R colony… …   Wikipedia

  • Colony-stimulating factor — A laboratory made agent similar to a substance in the body that stimulates the production of blood cells. Treatment with colony stimulating factors (CSFs) can help the blood forming tissue recover from the effects of chemotherapy and radiation… …   Medical dictionary

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